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. 2018 Jun 2;103(12):1138–1144. doi: 10.1136/archdischild-2017-314541

Table 3.

OR for different wheezing trajectories (early-remittent wheeze, late wheeze and persistent/relapsing wheeze) by gestational age group

Asthma trajectories Gestational age groups
<32 weeks;
very preterm
32–33 weeks;
moderate preterm
34–36 weeks;
late preterm
37–38 weeks;
early term
39–41 weeks;
full term
No wheeze (no wheezing at 3, 5, 7 and 11) n=50 (41.3%) n=58 (55.4%) n=349 (61.0%) n=1317 (66.1%) n=4784 (67.4%)
Early-remittent wheeze (only wheeze at 3 and/or 5) n=27 (25.2%) n=24 (19.1%) n=119 (19.4%) n=324 (16.7 %) n=1072 (15.5%)
 Relative risk ratio (95% CI)* 2.72 (1.49 to 4.96) 1.52 (0.89 to 2.60) 1.38 (1.10 to 1.74) 1.11 (0.94 to 1.29) 1
Late wheeze (only wheeze at 7 and/or 11) n=13 (8.7%) n=11 (7.9%) n=26 (5.7%) n=135 (5.6%) n=481 (6.8%)
 Relative risk ratio (95% CI)* 2.19 (1.04 to 4.62) 1.42 (0.71 to 2.86) 0.91 (0.58 to 1.42) 0.85 (0.66 to 1.09) 1
Persistent/relapsing wheeze (wheeze in early life at ages 3 and/or 5, and later in life at ages 7 and/or 11) n=29 (24.8%) n=19 (17.6%) n=80 (13.9%) n=239 (11.6%) n=761 (10.3%)
 Relative risk ratio (95% CI)* 4.30 (2.33 to 7.91) 2.06 (1.16 to 2.69) 1.45 (1.09 to 1.94) 1.15 (0.97 to 1.38) 1

Unweighted counts and survey-weighted proportions reported.

*Adjusted for child’s sex, ethnicity and age at interview; family history of asthma, household’s national statistics socioeconomic classification, maternal age at delivery, lone parent family and alcohol use during pregnancy.