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. 2018 Oct 1;71(12):1078–1083. doi: 10.1136/jclinpath-2018-205362

Table 1.

Summary of agreement between PD-L1 IHC 22C3 and 28-8 assays

All biopsies (n=1930)
n (%)
Biopsies with a confirmed lung cancer diagnosis (n=412)
n (%)
PD-L1 IHC difference 0%–10% 1825 (94.6) 393 (95.4)
PD-L1 IHC difference 11%–20% 60 (3.1) 10 (0.5)
PD-L1 IHC difference >20% 45 (2.3) 9 (2.2)
PD-L1 IHC difference 22C3=28-8 1589 (82.3) 340 (82.5)
PD-L1 IHC difference 22C3<28-8 132 (6.8) 27 (6.6)
PD-L1 IHC difference 22C3>28-8 209 (10.8) 45 (10.9)

IHC, immunohistochemistry; PD-L1, programmed death ligand 1.