Fig. 1.

Motility modulation of H. contortus L3 larvae exposed to levamisole, pyrantel or ivermectin. The automated larval migration assay (ALMA) was used to determine dose-dependent paralysis effect of Lev, Pyr or Ivm on the H. contortus L3 from Weybridge (A; C and E) or Kokstad isolate (B; D and F). Representative recording traces of the real-time fluorescence counting relative to the L3 migration during 5 min exposed to Lev (A and B); Pyr (C and D) or Ivm (E and F). Each trace corresponds to the mean data from 3 runs performed with 7500 L3 larvae. The controls correspond to untreated L3 larvae.