Table 3.

Multivariate Analysis of the Association Between eLP‐IR and Genetics and Fibrosis Stage in NAFLD

	Univariate Analysis			Multivariate Analysis
	β	95% CI	P Value	β*	95% CI	P Value
Conventional
Age	0.02	0.004 to 0.03	0.01	0.02	0.001 to 0.03	0.04
Sex (% female)	−0.04	−0.42 to 0.33	0.82	−0.36	−0.7 to ‐0.03	0.03
BMI	0.04	0.01 to 0.07	0.003	0.04	0.01 to 0.06	0.01
Hypertension	0.82	0.47 to 1.16	<0.001	0.45	0.07 to 0.83	0.02
Diabetes	1.04	0.67 to 1.41	<0.001	0.65	0.24 to 1.05	0.002
ALT (IU/L)	0.005	0.00 to 0.01	0.01	0.01	0.001 to 0.01	0.01
Pathogenesis based
eLP‐IR	0.01	0.004 to 0.02	0.004	0.01	0.001 to 0.02	0.03
PNPLA3 CC	REF			REF
CG	0.37	−0.05 to 0.78	0.09	0.18	−0.2 to 0.56	0.36
GG	0.34	−0.16 to 0.84	0.18	0.37	−0.07 to 0.82	0.1
TM6SF2 CC	REF			REF
CT or TT	0.07	−0.36 to 0.49	0.75	0.03	−0.34 to 0.4	0.87

^*Adjusted β coefficient calculated from multivariate models with all variables in this table.

Abbreviation: REF, reference.