Dissecting microscope images of the Epha2-null, Efna5-null, and Epha2/Efna5-null mouse lens phenotypes (P21). (A-F) Anterior-pole view of wild-type (A), Epha2-null (B, C), Efna5-null (D, E), and Epha2/Efna5-null (F) lenses under dark-field illumination. Epha2-null lenses (B, C) and Efna5-null lenses (D, E) exhibited variable translucent regions of internal refractive disturbance (white arrows) while mostly transparent. Epha2/Efna5-null lenses (F) were also mostly transparent but also exhibited anterior polar opacities in ~50% of cases (red arrow). Scale bar: 300 μm. (n = 18, 14, 8, and 8 for wild-type, Epha2-null, Efna5-null, and Epha2/Efna5-null lenses, respectively, with representative images shown).