Table 3.
Multivariate analysis of factors potentially associated with overall survival
| Model 1 (TLC included) | Model 2 (NLR included) | Model 3 (PLR included) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Characteristics | |||||||||
| Age ≥65 years | 1.51 | 0.88–2.41 | 0.185 | 1.43 | 0.87–2.35 | 0.176 | 1.43 | 0.89–2.35 | 0.175 |
| KPS score ≥70 | 1.68 | 1.04–3.63 | 0.041 | 1.53 | 1.13–3.24 | 0.032 | 1.52 | 1.1–3.23 | 0.033 |
| TNM stage IIIB | 1.32 | 0.44–2.43 | 0.162 | 1.84 | 0.71–2.82 | 0.148 | 1.82 | 0.74–2.85 | 0.143 |
| Pretreatment TLC ≥2.4×103/μL | 0.49 | 0.33–0.95 | 0.041 | ||||||
| Pretreatment NLR ≥3.4 | 1.66 | 1.05–2.79 | 0.041 | ||||||
| Pretreatment PLR ≥136.1 | 1.67 | 1.09–2.78 | 0.038 | ||||||
Abbreviations: HR, hazard ratio; KPS, Karnofsky Performance Status; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; TLC, total lymphocyte count.