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Cystoisospora belli is characterized by a distinctive parasitopherous vacuole (A, H&E, ×1,000), and is highlighted by periodic acid-Schiff-diastase (PASD) (B, ×1,000) and Alcian blue histochemical stains (C, ×1,000). Hyaline globules represent one histologic mimic (D, H&E, ×1,000) and also stain positive with PASD (E, ×1,000), but are consistently negative for Alcian blue (F, ×1,000).
