Table 6.
R50 [%] | R500 [%] | R5000 [%] | n | |
---|---|---|---|---|
WTS | 41.1 ± 1.84 | 20.7 ± 2.05 | 13.5 ± 2.09 | 35 |
RHS | 46.6 ± 3.45 | 19.5 ± 3.73 | 15.1 ± 3.54 | 9 |
WTL | 69.7 ± 3.94 | 24.8 ± 3.50 | 11.1 ± 2.94 | 10 |
RHL | 67.1 ± 3.59 | 21.6 ± 3.75 | 13.6 ± 3.62 | 12 |
All values are presented as mean ± S.E.M. Number of independent transfections >3. ICa inactivation normalized to Imax was obtained 50, 500 and 5000 ms after depolarization to Vmax. Statistical analysis was performed using unpaired Student’s t-test in comparison to WTS or WTL. n, number of experiments; R, remaining current; WT, wild-type.