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. Author manuscript; available in PMC: 2018 Dec 10.
Published in final edited form as: Genet Med. 2018 Jun 8;21(1):71–80. doi: 10.1038/s41436-018-0018-4

Figure 3. Estimates of the proportion of damaging missense variants by position in each gene.

Figure 3.

The AAPOS x-axis represents the amino acid position, and the y-axis is the probability of a missense mutation being damaging from the NVM model. The lines were smoothed using a 50 amino acid sliding window.