Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 1;8(1):e1486953. doi: 10.1080/2162402X.2018.1486953

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

PMC Copyright notice

Figure 2. — Intratumoral chemokine expression after sipuleucel-T treatment (n = 14). (A) Differential expression of immune-related genes in high vs. low CD8 T cell infiltrated cases are shown. Chemokine-related genes are shown in red. The X-axis represents log fold-difference which estimates a gene’s differential expression (2^(log fold change)-fold). (B) Localization of CXCL10 mRNA (green) and CD8a mRNA (red) expressing cells in the tumor microenvironment. The following probes were used in in situ hybridization. Negative control: DapB (bacterial dihydrodipicolinate reductase); positive control (green): POLR2A (encoding DNA-directed RNA polymerase II subunit RPB1); positive control (red): PPIB (human peptidylprolyl isomerase B). The section stained for CXCL10/CD8a is representative of fourteen cases.