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. 2018 Dec 10;13(12):e0208340. doi: 10.1371/journal.pone.0208340

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© 2018 De Meulenaere et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — a-b. In vivo serial T2w MRI scans in the same rat (a) and mouse (b) showing metastasis development as soon as 3 weeks after intracardiac injection (metastases are indicated with an arrow). c-d. T2w MR image (c) and T1w MR image after Gd enhancement (d) both acquired in a rat brain 6 weeks after intracardiac injection (metastases are indicated with an arrow). e. Histological confirmation of metastasis by H&E staining on paraffin-embedded slices in the cerebellum of a rat.