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. 2018 Nov 12;29(12):2835–2846. doi: 10.1681/ASN.2018030263

Table 3.

Adjusted odds ratios and 95% confidence intervals of the association of BP trajectory groups with subclinical kidney damage

Trajectory Groups No. of Subjects with SRD in 2017 (%) Unadjusted Model 1 Model 2 Model 3
SBP trajectory group
 Low stable 42 (7.85) 1.00 1.00 1.00 1.00
 Moderate stable 98 (10.99) 1.45 (0.99 to 2.12) 1.19 (0.79 to 1.78) 1.16 (0.77 to 1.74) 1.10 (0.73 to 1.67)
 High stable 47 (21.66) 3.25 (2.07 to 5.10) 2.12 (1.29 to 3.49) 1.76 (1.03 to 2.99) 1.63 (0.95 to 2.81)
 Moderate increasing 41 (43.62) 9.08 (5.42 to 15.20) 5.03 (2.86 to 8.87) 3.21 (1.70 to 6.08) 3.04 (1.58 to 5.85)
DBP trajectory group
 Low stable 67 (7.94) 1.00 1.00 1.00 1.00
 Moderate stable 52 (11.71) 1.54 (1.05 to 2.25) 1.30 (0.86 to 1.96) 1.23 (0.81 to 1.87) 1.16 (0.76 to 1.78)
 High stable 58 (17.63) 2.48 (1.70 to 3.62) 1.82 (1.19 to 2.78) 1.74 (1.13 to 2.68) 1.63 (1.04 to 2.53)
 Moderate increasing 51 (42.15) 8.45 (5.45 to 13.10) 5.27 (3.22 to 8.63) 3.43 (1.93 to 6.12) 3.38 (1.87 to 6.12)
MAP trajectory group
 Low stable 47 (6.93) 1.00 1.00 1.00 1.00
 Moderate stable 98 (12.41) 1.90 (1.32 to 2.74) 1.47 (0.98 to 2.19) 1.44 (0.96 to 2.16) 1.33 (0.88 to 2.01)
 High stable 37 (23.42) 4.11 (2.56 to 6.59) 2.73 (1.62 to 4.60) 2.37 (1.36 to 4.11) 2.29 (1.30 to 4.03)
 Moderate increasing 46 (41.07) 9.36 (5.80 to 15.11) 5.42 (3.17 to 9.28) 3.67 (1.96 to 6.87) 3.37 (1.76 to 6.43)

Model 1 = sex, race, body mass index, heart rate, and waist-to-hip ratio in 2017. Model 2 = model 1 + hypertension, diabetes, hyperlipidemia, smoking, and drinking in 2017. Model 3 = model 2 + fasting blood glucose (millimoles per liter), serum uric acid (micromoles per liter), total cholesterol (millimoles per liter), triglycerides (millimoles per liter), LDL (millimoles per liter), and HDL (millimoles per liter) in 2017. SBP, systolic BP; DBP, diastolic BP; MAP, mean arterial pressure.