Fig 2. Effect of melanoma subtype on nucleosome-associated mutation patterns.

Enrichments of mutations occurring in dipyrimidines in (A) acral melanomas (B) cutaneous melanomas, or (C) prostate cancer were calculated at nucleosome positions. The cutaneous, but not acral or prostate, mutation enrichment exhibits the same ~10 bp periodicity. As shown in S2 Fig, this was not due to a difference in power.