Figure 2.

¹³C–¹³C and ¹³C–¹⁵N correlation spectra of (a) Q44-HttEx1 and (b) D₂Q₁₅K₂ fibrils. Two types of Gln that compose the polyQ core are annotated in purple and cyan, while polyproline helix and random coil prolines are annotated in red and orange, respectively. TEM micrographs of the fibril samples are shown as insets. ¹³C assignments for oligoproline and polyQ regions are labeled in red and black in panels a and b, respectively. Only one set of assignments is shown in panels a and b for clarity.