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. 2018 Dec 10;13(12):e0208947. doi: 10.1371/journal.pone.0208947

Fig 1. Purine de novo synthesis in humans.

Fig 1

Abbreviations: phosphoribosylamine (PRA), glycinamideribonucleotide (GAR), N-formylglycinamide ribonucleotide (FGAR), N-formylglycinamidine ribonucleotide (FGAMR), aminoimidazole ribonucleotide (AIR), carboxyaminoimidazole ribonucleotide (CAIR), N-succinocarboxamide-5-aminoimidazole ribonucleotide (SAICAR), 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), 5-formamido-4-imidazolecarboxamide ribonucleotide (FAICAR), inosine-5-monophosphate (IMP), glutamine (Gln), glutamate (Glu), pyrophosphate (PPi), adenosine-5'-triphosphate (ATP), adenosine 5'-diphosphate (ADP), glycine (Gly), phosphate (Pi), N10-formyl tetrahydrofolate (N10-formyl THF), tetrahydrofolate (THF), hydrogen carbonic acid (HCO3-), aspartate (Asp). For enzyme abbreviations, see the second paragraph of the Introduction.