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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Expert Rev Cardiovasc Ther. 2018 Jul 16;16(8):579ā€“589. doi: 10.1080/14779072.2018.1497485

Table 1:

Common echocardiographic parameters used in the assessment of diastolic function.

Parameter Definition Application to DD
E Mitral flow velocity during early diastole Representative of the pressure gradient between atrium and ventricle. Related to ventricular relaxation and left atrial pressure.
A Mitral flow velocity during late diastole Representative of the pressure gradient between atrium and ventricle. Related to ventricular wall compliance and atrial contractility.
E/A ratio Ratio between mitral flow velocities during early and late diastole Representative of filling patterns, with low ratios suggestive of restricted filling and high ratios suggestive of poor relaxation.
eā€™ Mitral annular velocity during early diastole Primarily representative of ventricular relaxation. Found to be related to tau, the time constant of ventricular pressure decay.
E/eā€™ ratio Ratio between mitral flow and mitral annular velocities during early diastole Representative of ventricular filling pressures during diastole by correcting for ventricular relaxation.
TR velocity Peak velocity of tricuspid regurgitation during systole Representative of left atrial pressures, in absence of pulmonary hypertension.
LAVI Maximum left atrial volume Representative of structural changes in the atrium due to increased pressures.

The above information is collected and tabulated from the publication of Nagueh et al. [30]; DD, diastolic dysfunction; TR, tricuspid regurgitation; LAVI, left atrial maximal volume index.