Table 1:
Parameter | Definition | Application to DD |
---|---|---|
E | Mitral flow velocity during early diastole | Representative of the pressure gradient between atrium and ventricle. Related to ventricular relaxation and left atrial pressure. |
A | Mitral flow velocity during late diastole | Representative of the pressure gradient between atrium and ventricle. Related to ventricular wall compliance and atrial contractility. |
E/A ratio | Ratio between mitral flow velocities during early and late diastole | Representative of filling patterns, with low ratios suggestive of restricted filling and high ratios suggestive of poor relaxation. |
eā | Mitral annular velocity during early diastole | Primarily representative of ventricular relaxation. Found to be related to tau, the time constant of ventricular pressure decay. |
E/eā ratio | Ratio between mitral flow and mitral annular velocities during early diastole | Representative of ventricular filling pressures during diastole by correcting for ventricular relaxation. |
TR velocity | Peak velocity of tricuspid regurgitation during systole | Representative of left atrial pressures, in absence of pulmonary hypertension. |
LAVI | Maximum left atrial volume | Representative of structural changes in the atrium due to increased pressures. |
The above information is collected and tabulated from the publication of Nagueh et al. [30]; DD, diastolic dysfunction; TR, tricuspid regurgitation; LAVI, left atrial maximal volume index.