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Gray matter volume (GMV) reduction with (a) age and (b) prolonged SSRT (blue), and (c) both age and prolonged SSRT (cyan). (d) GMV reduction in bilateral insula, right inferior and middle frontal gyri, and right caudate head completely mediated the relationship between age and prolonged SSRT [Color figure can be viewed at http://wileyonlinelibrary.com]
