Skip to main content
. Author manuscript; available in PMC: 2018 Dec 10.
Published in final edited form as: J Ocul Dis Ther. 2017;5:19–27.

Figure 2.

Figure 2

Corneal levels of IL-2, IL-9, IL-12p40 and VEGF are down regulated by corneal abrasion and also during re-epithelialization. A 2 mm circular epithelial abrasion was created on the mouse cornea. The abrasions were treated with vehicle (saline) or CAP37 in saline as an eye drop at 0 and 16 h. Corneas were collected and flash frozen at indicated times post corneal abrasion. Corneal lysates were analyzed for cytokines using the Milliplex® MAP mouse cytokine assay. The mean of 4 to 6 independent values obtained from 4 to 6 mice are shown ± SEM. The unwounded corneas were compared to wounded saline treatment and to wounded CAP37 treatment corneal samples for each time point using two-way ANOVA and Tukey’s multiple comparisons test, *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.0001.