Table 2.

Biologically averaged concentrations of the radiation biomarkers. The 6 Gy to 7 Gy range corresponds to the LD30 to LD50 exposure for the rhesus macaque NHP species. The biological variation (SEM) is higher at 6 or 7 Gy than at either lower or higher exposures for creatine, TML, xanthine, and xanthurenic acid, as shown in Figure 3. (TML is N6,N6,N6-trimethyl-L-lysine, iBCAR is isobutyrylcarnitine).

Biological average concentration
		------------------------------------- μM ---------------------------------						mM
Dose(Gy)	Samples	creatine	hypoxanthine	TML	iBCAR	xanthine	xanthurenic acid	creatinine
0	3	434.2	132.6	98.8	31.9	176.6	45.6	27.1
2	3	144.7	152.6	50.8	34.7	223.7	54.8	15.9
4	3	312.2	85.0	99.3	39.3	192.6	59.3	19.6
6	3	992.1	118.9	36.9	31.5	163.7	78.9	11.3
7	3	4623.1	134.7	1543.6	13.9	520.2	100.8	20.0
10	2	8155.0	141.5	1193.2	0.8	470.2	233.8	–
Standard error of the mean (SEM)
		------------------------------------- μM ---------------------------------						mM
Dose(Gy)	Samples	creatine	hypoxanthine	TML	iBCAR	xanthine	xanthurenic acid	creatinine
0	3	131.43	18.63	11.94	10.07	36.91	8.01	8.14
2	3	22.54	38.39	15.96	2.18	15.89	5.95	1.10
4	3	127.73	29.22	55.97	13.70	43.67	9.16	3.99
6	3	733.97	43.58	9.77	8.52	48.19	6.66	1.29
7	3	1424.59	22.60	779.95	9.68	167.00	76.48	6.80
10	2	817.85	42.95	124.21	1.82	59.22	46.06	–