Table 2.
Reported Cases of Neuropathy with Anti-ganglioside Antibody Associated with Lung Cancer.
| Case | Reference | Age, Sex | Histology | Progression | Neuropathy | Consistent with GBS | CSF, cell number, protein (mg/dL) | Antibodies | Treatment (improvement of neuropathy) | Prognosis, months from onset of cancer |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 9 | 62, F | Small | Subacute | Sensorimotor | No | 5, 131 | GM1-IgM | Steroid (No), Chemotherapy (No), IVIg (Yes) | Died, 11 |
| 2 | 10 | 73, M | Adeno | Chronic | Motor, Axonal | No | Normal, Normal | IgG1 and IgG3 to GD1a and GM1 | Steroid & IVIg (No) | Died, 6 |
| 3 | 7 | 84, M | ND | Subacute | Axonal | No | ND | GM1 | ND | ND |
| 4 | 11 | 67, M | Small | Acute | Motor | Yes | 0, 25 | GM1-IgG | IVIg (No), chemotherapy (Temporary) | Died, 5 |
| 5 | Present case | 66, M | Small | Subacute | Sensorimotor, Urinary & fecal incontinence | No | 19, 116 | GM1-IgM | Chemotherapy & IVIg (Minimal) | Died, 18 |
GBS: Guillain-Barré syndrome, CSF: cerebrospinal fluid, IVIg: intravenous immunoglobulin, ND: not described