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. 2018 Dec 10;8:17753. doi: 10.1038/s41598-018-36026-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of SDS root ESF on FeCl₃ induced rat plasma levels of TXB₂ and 6-keto-PGF_1α. (A) TXB₂/6-keto-PGF_1α ratio; (B) and vWF (C). Before the establishment of FeCl₃-induced rat carotid artery thrombosis models, rats in each group were lavaged with different doses of SDS root EtOAc extract or CDDP for 20 days, once a day. n = 10; data are presented as the mean ± SD; *P < 0.05, significant difference compared to the model group; ^ΔP < 0.05 compared to the sham group.