. 2018 Dec 10;8:123. doi: 10.1186/s13613-018-0470-y

Table 4.

Subgroup analyses of primary outcomes

Outcomes	No. of trials (PAV/NAVA)	Total sample size	Summary estimates (95% confidence intervals)	Heterogeneity			p value (test for subgroup difference)
Outcomes	No. of trials (PAV/NAVA)	Total sample size	Summary estimates (95% confidence intervals)	Q	df	I² (%)	p value (test for subgroup difference)
AI as continuous outcome	PAV, 1	32	WMD − 0.45 (− 1.00, 0.10)	0.00	0	–	0.06
AI as continuous outcome	NAVA, 7	268	WMD − 3.06 (− 5.74, − 0.39)	35.53	6	83.1
AI > 10%	PAV, 2	110	RR 0.06 (0.01, 0.46)	0.00	1	0.0	0.57
AI > 10%	NAVA, 5	151	RR 0.20 (0.05, 0.92)	15.47	4	59.5
Weaning failure	PAV, 3	317	RR 0.44 (0.26, 0.75)	0.60	2	0.0	NA
Duration of mechanical ventilation	PAV, 3	318	WMD − 2.25 (− 3.86, − 0.65)	3.13	2	36.5	0.16
Duration of mechanical ventilation	NAVA, 2	161	WMD − 0.03 (− 2.66, 2.61)	0.03	1	0.0

AI asynchrony index, RR risk ratio, WMD weighed mean difference