Table 1.

Genome-wide significant (5 × 10⁻⁹) loci associated with accelerometer-measured physical activity and sleep duration behaviours in 91,105 UK Biobank participants

Status	Trait	ID	Ch	SNP	Position	Nearest gene	Allele (effect/other)	EAF	Beta	SE	p
Novel	Overall activity	1	10	rs564819152	21,820,650	SKIDA1	A/G	0.679	0.028	0.005	4.20E-09
Novel	Sleep duration	2	9	rs2416963	128,241,414	MAPKAP1	C/T	0.589	0.030	0.005	2.30E-10
Novel	Sleep duration	3	7	rs2006810	69,902,152	AUTS2	T/C	0.604	-0.028	0.005	3.90E-09
Novel	Sedentary	4	5	rs26579	87,985,295	MEF2C-AS2	G/C	0.415	0.028	0.005	2.60E-09
Novel	Sedentary	5	5	rs25981	106,822,908	EFNA5	G/C	0.531	0.028	0.005	3.00E-09
Novel	Sedentary	6	3	rs1858242	68,527,135	LOC105377146	A/G	0.259	0.031	0.005	3.10E-09
Novel	Sedentary	7	7	rs34858520	71,723,883	CALN1	A/G	0.558	0.028	0.005	4.20E-09
Known8	Overall activity	8	17	rs2696625	44,326,864	KANSL1-AS1	A/G	0.77	-0.037	0.005	3.20E-12
Known8	Overall activity	9	18	rs59499656	40,768,309	SYT4	A/T	0.655	-0.028	0.005	1.90E-09
Known Neale,12,18,21,23,24	Sleep duration	10	2	rs62158170	114,082,175	PAX8-AS1	A/G	0.783	-0.051	0.006	5.80E-20
Known18,23	Sleep duration	11	2	rs113851554	66,750,564	MEIS1	G/T	0.943	0.090	0.010	3.10E-18
Known23	Sleep duration	12	6	rs72828533	19,065,680	LOC101928519	A/T	0.818	0.043	0.006	2.70E-13
Known12,24	Sleep duration	8	17	rs7502280	43,670,221	MAPK8IP1P2	T/G	0.867	0.051	0.008	8.80E-11
Known Neale,21,24	Sleep duration	13	19	rs2303100	9,968,434	OLFM2	C/T	0.447	-0.030	0.005	1.40E-10
Known Neale, 23,24	Sleep duration	14	1	rs75641275	98,327,133	DPYD	A/C	0.859	0.042	0.007	2.20E-10

Beta and SE are in standard deviation units

EAF  effect allele frequency, Ch  chromosome