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. 2018 Dec 4;9:2911. doi: 10.3389/fmicb.2018.02911

FIGURE 6.

FIGURE 6

Model of the structure of formate dehydrogenase coupled hydrogenases. FHL of E. coli (A) has the physiological function of formate oxidation coupled to H2 formation. The FHL consist of a [NiFe] hydrogenase coupled to a formate dehydrogenase and membrane integral subunits. In contrast, the HDCR of A. woodii (B) is composed of a [FeFe] hydrogenase coupled to a formate dehydrogenase and catalyzes reversible CO2 reduction with H2 as electron donor.