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. 2018 Dec 4;9:1389. doi: 10.3389/fphar.2018.01389

FIGURE 7.

FIGURE 7

Aurantio-obtusin blocks ASM contraction. (A) Separation of EESC components and the standard aurantio-obtusin were analyzed with HPLC. One peak of EESC overlapped with that of the standard aurantio-obtusin. These experiments were conducted twice, and the same results were acquired. (B,C) aurantio-obtusin blocked the contraction of ASM from TRs induced by ACh and high K+, and from lung slices provoked by ACh. These results indicate that aurantio-obtusin, which is one component of EESC, inhibits ASM contraction.