Table 3.
Summary of significantly overrepresented pathways related with lipid metabolism in the DE genes between H and L groups.
| Term | Genes | Adjusted p-value |
|---|---|---|
| GOBP | ||
| Response to fatty acid (GO:0070542) | CTGF, ADCY6, ADIPOQ, DGAT2 | 1.38 × 10-4 |
| Triglyceride metabolic process (GO:0006641) | ELOVL6, THRSP, FASN, PLIN1, DGAT2 | 3.75 × 10-4 |
| Neutral lipid metabolic process (GO:0006638) | ELOVL6, THRSP, FASN, PLIN1, DGAT2 | 4.27 × 10-4 |
| Fat pad development (GO:0060613) | ARID5B, DGAT2 | 8.77 × 10-4 |
| Triglyceride biosynthetic process (GO:0019432) | ELOVL6, THRSP, FASN, DGAT2 | 0.001 |
| Neutral lipid biosynthetic process (GO:0046460) | ELOVL6, THRSP, FASN, DGAT2 | 0.002 |
| Long-chain fatty-acyl-CoA metabolic process (GO:0035336) | ELOVL6, FASN, DGAT2 | 0.002 |
| Fatty-acyl-CoA metabolic process (GO:0035337) | ELOVL6, FASN, DGAT2 | 0.003 |
| Adipose tissue development (GO:0060612) | ARID5B, DGAT2 | 0.003 |
| Long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) | ELOVL6, FASN | 0.003 |
| Fatty-acyl-CoA biosynthetic process (GO:0046949) | ELOVL6, FASN | 0.003 |
| GOSLIM | ||
| Lipid particle (GO:0005811) | CIDEC, PLIN1, DGAT2 | 0.003 |
| Recon | ||
| Fatty_acid_elongation | FASN, SCD | 0.003 |
GOBP, biological process; GOSLIM, cut-down versions of the GO ontologies containing a subset of the terms in GO; Recon, Genome-Scale Metabolic Network.