Table 4.

Top three networks enriched with DE genes detected by IPA software.

			Focus
ID	Molecules in network	Score	molecules	Top functions
1	26S proteasome, ACTC1, actin, AHSP, ARHGEF4, ARHGEF6, ASB10, BCR (complex), BRD8, caspase, cofilin, DMD, F actin, Hdac, HDAC9, HISTONE, histone deacetylase, Histone h3, Histone h4, Hsp70, Hsp90, Jnk, JUNB, LMO7, MYL12A, Nos, P glycoprotein, PRSS8, Raf, RHOD, RNA polymerase II, RPRM, SDR16C5, SIRT3, UCK2	31	17	Cell Morphology, Organ Morphology, Skeletal and Muscular System Development and Function
2	ADRB, ANKRD1, BMP, CA9, Cdc2, Cdk, Cyclin A, ERCC5, ESRRG, Fascin, FST, GADD45, GADD45A, GADD45B, GADD45G, growth factor, JUN/JUNB/JUND, MAP3K, MYF6, NF-κB (complex), Notch, P-TEFb, Pak, PP1 protein complex group, PPP1R15A, Ppp2c, Rb, Sapk, Serine Protease, TNKS1BP1, TNNI1, TP53BP2, TRAFD1, TRIM55, USP28	29	16	Cell Cycle, Cellular Growth and Proliferation, Cellular Development
3	Adaptor protein 1, ADRA1, C/ebp, CD3 group, CIDEC, CPT1, DGAT2, dynamin, ELOVL6, ERK1/2, FASN, FOSB, GOT, GPAT3, JINK1/2, N-cor, NFAT (complex), Nr1h, p70 S6k, PEPCK, Pkg, PLIN1, PRDX2, PRKAA, Rar, Rxr, SCD, SEMA4D, SH3GLB2, SHB, SYK/ZAP, TCF, THRSP, thyroid hormone receptor, TSH	22	13	Lipid Metabolism, Small Molecule Biochemistry, and Carbohydrate Metabolism

DE genes between H and L groups in bold.