Table 6.
Potential regulators affecting gene expression of DE genes between H and L groups, identified by RIFs study and IPA software.
| Gene symbol | Gene | RIF1¥ | RIF2† | IPA-regulators p-value |
|---|---|---|---|---|
| ARID5B | ARID Domain-Containing Protein 5B | -0.10 | -2.40 | – |
| ATF3 | Activating Transcription Factor 3 | -0.05 | -2.23 | 0.002 |
| EGR1 | Early Growth Response 1 | -0.30 | -2.18 | 2.27 × 10-07 |
| EGR2 | Early Growth Response 2 | -0.23 | -2.32 | 0.015 |
| EGR3 | Early Growth Response 3 | -1.70 | -2.00 | – |
| FOS | Fos Proto-Oncogene, AP-1 Transcription Factor Subunit | 0.00 | -1.87 | 4.76 × 10-08 |
| JUNB | JunB Proto-Oncogene, AP-1 Transcription Factor Subunit | 0.60 | -1.34 | 1.23 × 10-05 |
| KLF11 | Kruppel Like Factor 11 | -2.30 | -0.92 | – |
| MYC | MYC Proto-Oncogene, BHLH Transcription Factor | -1.70 | -1.91 | 0.003 |
| MYF6 | Myogenic Factor 6 | 0.10 | -2.33 | – |
| POU3F1 | POU Class 3 Homeobox 1 | -1.46 | -0.81 | – |
| TRAFD1 | TRAF-Type Zinc Finger Domain Containing 1 | -0.23 | -2.33 | – |
¥Bootstrap 99% confidence intervals for RIF1 z-scores: -1.193/2.352. †Bootstrap 99% confidence intervals for RIF2 z-scores: -1.223/1.648.