TABLE 5.
V3 characteristics and coreceptor tropisma
| Sequence name | Length (aa) | Net chargeb |
Total chargec |
PNGSd | L18Ze | V19K/Re | Net>+6e | Ins24e | Predicted tropismf |
|---|---|---|---|---|---|---|---|---|---|
| TD024 | 34 | 5 | 5 | 1 | N | N | N | N | R5 |
| TD031 | 34 | 5 | 5 | 1 | N | N | N | N | R5 |
| TD062 | 34 | 5 | 5 | 1 | N | N | N | N | R5 |
| CBL20 | 34 | 6 | 6 | 1 | N | N | N | N | R5 |
| RODR | 36 | 7 | 7 | 1 | N | N | Y | N | R5X4 |
| A.CI.UC2 | 35 | 7 | 7 | 1 | N | N | Y | Y | R5X4 |
| A.DE.BEN | 34 | 5 | 5 | 1 | N | N | N | N | R5 |
| A.DE.PEI2 | 35 | 7 | 9 | 1 | N | Y | Y | Y | R5X4 |
| A.GH.GH1 | 34 | 5 | 5 | 1 | N | N | N | N | R5 |
| A.GM.D194 | 35 | 8 | 8 | 1 | N | N | Y | Y | R5X4 |
| A.GM.ISY_SBL | 35 | 8 | 10 | 1 | N | N | Y | Y | R5X4 |
| A.GM.MCN13 | 35 | 7 | 7 | 1 | N | N | Y | Y | R5X4 |
| A.GM.MCR35 | 35 | 7 | 7 | 1 | N | N | Y | Y | R5X4 |
| A.GW.CAM2CG | 34 | 6 | 6 | 1 | N | N | N | N | R5 |
| A.GW.MDS | 34 | 6 | 6 | 1 | N | N | N | N | R5 |
| A.GW.NIHZ | 35 | 7 | 7 | 1 | N | N | Y | Y | R5X4 |
| A.IN.CRIK_147 | 35 | 7 | 7 | 1 | N | N | Y | Y | R5X4 |
| A.IN.NNVA | 34 | 5 | 5 | 1 | Y | N | N | N | R5X4 |
| A.JP.NMC786_41 | 35 | 6 | 6 | 1 | N | N | N | Y | R5X4 |
| A.JP.NMC786_43 | 35 | 6 | 6 | 1 | N | N | N | Y | R5X4 |
| A.PT.ALI | 34 | 6 | 6 | 1 | N | N | N | N | R5 |
| A.SN.ROD | 36 | 7 | 7 | 1 | N | N | Y | N | R5X4 |
| A.SN.ST_JSP4_27 | 34 | 6 | 6 | 1 | N | N | N | N | R5 |
a
Coreceptor tropism was assessed as described in reference 59.
b
Net charge of sequences was determined based on each lysine and arginine contributing +1 and each aspartic acid and glutamic acid contributing −1.
c
Total counts of amino acids were also assessed as described previously (58).
d
Number of potential N-linked glycosylation sites (PNGS) as defined in N-GLYCOSITE (37).
e
N, no; Y, yes.
f
R5, CCR5-using virus; R5X4, CCR5- and CXCR4-using virus.