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. 2018 Dec 4;6:190. doi: 10.3389/fbioe.2018.00190

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Copyright © 2018 Cimmino, Rossano, Netti and Ventre.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Set of cyclic RGD peptides tethered to a photoswitchable 4-[(4-aminophenyl)azo]benzocarbonyl unit. Spacer length varies according to m or n value and on the isomerization of the switch. (B) Effects of spacer length and conformation on MC3T3 adhesion on PMMA. Substrates were irradiated for 3 h at 450 nm (dark gray column) and overnight at 366 nm (light gray column), respectively. Arrow indicates comparable level of cell adhesion with respect to the uncoated material (white column). Adapted with permission from Auernheimer et al. (2005). Copyright 2005 American Chemical Society.