Table 2.

Comparison of characters in DHEA-induced PCOS model of post-pubertal rats.

	Period of DHEA treatment(day after birth)	Mean body weight on end day (g)		Ratio (%) of rats with irregular estrus cycles (numbers)		Mean ovary weight (mg/each)		Ratio of rats with multi–cystic ovaries (numbers)		Mean uterus weight (g/cm)
		Sham	DHEA	Sham	DHEA	Sham	DHEA	Sham	DHEA	Sham	DHEA
Pubertal (60 mg/kg BW, s.c., SD rat)	42–63	247.0 ± 9.7	243.4 ± 5.7	0 (0/4)	100# (4/4)	39.7 ± 1.9	57.0 ± 1.5#	0 (0/4)	75 (3/4)	46.6 ± 2.7	116.8 ± 8.6#
	42–63	245.5 ± 7.5	249.2 ± 4.9	0 (0/4)	100## (5/5)	37.6 ± 1.1	67.8 ± 6.6#	0 (0/4)	80# (4/5)	47.3 ± 5.6	103.4 ± 15.4#
	42–62	266.2 ± 9.4	264.4 ± 6.9	0 (0/5)	100## (6/6)	44.4 ± 5.0	62.5 ± 4.6#	0 (0/5)	100## (6/6)	44.9 ± 2.2	105.2 ± 1.7##
	42–70	267.5 ± 10	254.8 ± 4.1	0 (0/4)	100# (4/4)	37.5 ± 1.5	77.6 ± 9.1#	0 (0/4)	75 (3/4)	51.5 ± 4.3	127.8 ± 12#
	42–72	282.3 ± 11.6	242.4 ± 14.0	0 (0/5)	70# (5/7)	49.5 ± 3.2	47.7 ± 6.4	0 (0/5)	70# (5/7)	71.2 ± 12.7	91.7 ± 7.4
	42–72	251.6 ± 7.9	250.0 ± 5.9	0 (0/5)	66.7 (4/6)	47.5 ± 2.1	55.1 ± 2.6#	0 (0/5)	100## (6/6)	71.6 ± 2.5	121.3 ± 4.3#
	42–62	219.3 ± 2.8	243.5 ± 4.0#	– (N/5)	– (N/5)	36.5 ± 2.0	63.4 ± 3.2##	0 (0/5)	80# (4/5)	54.0 ± 1.4	97.4 ± 3.0#
	42–62	245.9 ± 2.2	267.4 ± 4.6#	– (N/5)	– (N/5)	49.1 ± 3.2	67.9 ± 6.1	0 (0/5)	100## (5/5)	63.3 ± 5.4	105.2 ± 7.0#
	42–62	241.4 ± 5.6	262.9 ± 5.0#	– (N/5)	– (N/5)	39.7 ± 1.9	56.6 ± 1.5	0 (0/5)	100## (5/5)	67.3 ± 15.4	129.2 ± 4.0#
	42–62	235.4 ± 3.1	257.9 ± 5.8#	– (N/5)	– (N/5)	46.7 ± 1.2	62.7 ± 4.3##	0 (0/5)	80# (4/5)	64.1 ± 6.1	109.5 ± 7.5#
	42–62	223.7 ± 4.5	245.5 ± 0.9#	– (N/5)	– (N/5)	41.1 ± 4.1	67.0 ± 9.3#	0 (0/5)	80# (4/5)	60.6 ± 2.7	101.3 ± 5.3##
Mean	–	–	–	0 (0/27)	87.5## (28/32)	–	–	0 (0/52)	85.9## (49/57)	–	–

^#p < 0.05 and

^##p < 0.01 vs. Sham group. The “-” and “N”, not be identified.