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. 2018 Dec 4;6:164. doi: 10.3389/fcell.2018.00164

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Copyright © 2018 Gurung, Williams, Deane, Werkmeister and Gargett.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially expressed genes (DEGs) confirmed by Fluidigm qPCR. (A) MSC potency, (B) proliferation, (C) anti-proliferation, (D) fibroblast and (E) apoptosis-related genes were validated in control and A83-01 treated P6 eMSCs. Data points (black circles, A83-01-treated, white circles, control) and medians are shown. Panels above each graph shows the heat map of the corresponding genes in RNA seq (^∗p < 0.03, ^∗∗p < 0.002, n = 6–8).