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. 2018 Dec 6;6(15):961–984. doi: 10.12998/wjcc.v6.i15.961

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Funnel plot showing the relationship between the relative risk and its standard error for each of 11 studies used in a fixed effects meta-analysis with a moderator for concomitant drug therapy evaluating the effect of Medilac-S^® in combination with conventional drug therapy on number of reported clinical symptoms for (A) abdominal pain and (B) tenesmus.