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. 2018 Dec 6;6(15):961–984. doi: 10.12998/wjcc.v6.i15.961

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Forest plots of the results of fixed effects meta-analysis with 30 studies evaluating the effect of Medilac-S^® in combination with conventional drug therapy on number of participants reporting adverse events. “AE” is the number of participants reporting adverse events within a study and “N” is the total number of participants within the study. The relative risk (RR) and its 95%CI for each study are listed on the right hand side of the graph. The 95%CI for the estimated mean RR for each concomitant drug therapy category is shown as a shaded diamond with the endpoints of the diamond being the CI endpoints. The vertical dashed line at 1 indicates a RR of 1 which occurs when there is no observed difference between the treatment and the control.