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. 2018 Nov 27;2018:7108604. doi: 10.1155/2018/7108604

Figure 2.

Figure 2

MAT effects on D-gal-induced memory impairment in the novel object recognition test. MAT (2 and 10 mg/kg, oral) was administrated to D-gal-treated mice. D-gal was injected at a dose of 150 mg/kg for six weeks (s.c.). (a) Time spent on the object in seconds and (b) object recognition index were observed. Results are presented as mean ± SEM. n = 9, ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001, differences between recognition index in the training and test session. Control received 2% ethanol in saline + saline, D-gal received 2% ethanol in saline + 150 mg/kg D-gal, VE-100 received 100 mg/kg VE + 150 mg/kg D-gal, M-2 received 2 mg/kg matrine + 150 mg/kg D-gal, and M-10 received 10 mg/kg matrine + 150 mg/kg D-gal.