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. 2018 Nov 27;3(11):15952–15965. doi: 10.1021/acsomega.8b02526

Figure 2.

Figure 2

(A) Scheme of the synthesis of the pH-sensitive NCs: (i) distillation–precipitation polymerization method using MAA, 2,2′-azobisisobutyronitrile (AIBN), and N2 bubbling in ACN; (ii) distillation–precipitation polymerization method using MAA, PEGMA, MBA, and N2 bubbling in acetonitrile (ACN); and (iii) core removal in EtOH/H2O dist. (B) Scanning electron microscopy (SEM) pictures taken after each synthesis step: (I) PMAA cores; (II) PMAA@P(MAA-co-PEGMA-co-MBA); and (III) hollow P(MAA-co-PEGMA-co-MBA) NCs.