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. 2018 Dec 11;19(Suppl 8):861. doi: 10.1186/s12864-018-5195-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Ancestry-specific effects on gene expression. These results give an indication of how ancestry-enriched SNPs can impact health-related phenotypes by virtue of their gene regulatory effects. SNP-by-ancestry interactions were characterized using an expression quantitative trait loci (eQTL) approach. Examples of a African-specific and b European-specific eQTL are shown along with c eQTL shared between populations. d eQTL related to immune system and infectious disease found in the African and European populations are shown in a CIRCOS plot with links indicated between eQTLs and their regulated genes. e Examples of immune-related pathways that include multiple eQTL-regulated genes for African and/or European populations