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. 2018 Dec 10;18:1233. doi: 10.1186/s12885-018-5109-8

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Modulation of tumorigenesis in the MMTV-neu transgenic model for human luminal HER2+ breast cancer. (a) Disease-free survival curves for MMTV-neu;MD+/+ (n = 19), MMTV-neu;MD+/− (n = 11) and MD−/− (n = 11) mice. Log-rank test P-values are shown. (b) Average age at the appearance of the first palpable tumor. (c) Tumor growth plot graphing average diameter size (in mm) versus weeks after first appearance. (d) Average age at end point. (e) Average amount of lung macro-metastatic foci. * = p < 0.05