Table 4.
Information including number of patients included and analyzed and anchor used for each study selected (N = 46)
| Reference | Number of patients included | Number of patients included in the analysis (range for multiple analyses) | Questionnaires on which the MID was determined | Anchor |
|---|---|---|---|---|
| Askew, R.L. (2009) [19] | 273 | 163 | FACT-M | Performance status |
| Bédard, G. (2014) [21] | 369 | 367 to 369 | EORTC QLQ-C30 | Global HRQOL dimension of the QLQ-C30 |
| Bédard, G. (2016) [22] | 276 | 276 | EORTC QLQ-C15-PAL | Global HRQOL dimension of the QLQ-C15 PAL |
| Bédard, G. (2016) [22] | 421 | 197 to 276 | EDMONTON SYMPTOM ASSESSMENT SYSTEM (ESAS) | Well-being dimension of the ESAS |
| Bharmal, M. (2017) [23] | 88 | 70 | FACT-M | Percentage change in tumor size |
| Binenbaum, T. (2014) [24] | 1011 | 329 to 631 | UW-QOLQ, EORTC QLQ-C30, QLQ-H&N35 | No anchor used |
| Cella, D. (2009) [26] | 809 | 809 | FACT-P | Performance status |
| Cella, D. (2002) [13] | 50; | 50 to 2402 | FACT-AN | Performance status; hemoglobin level |
| Cella, D. (2002) [25] | 599 | 573 | FACT-L | Best overall response to treatment, time to disease progression |
| Chan, A. (2018) [27] | 257 | 201 | MFSI-SF | Fatigue dimension of the QLQ-C30 |
| Cheung, Y.T. (2014) [28] | 330 | 220 | FACT-Cog | Cognitive dimension of the QLQ-C30 |
| Den Oudsten, B.L. (2013) [29] | 606 | 355 | WHOQOL-100 | QoL of the WHOQoL |
| Eton, D.T. (2007) [32] | 92 | 91 | FACT-G, FACT-Lung Symptom Index-12 | Performance status |
| Eton, D.T. (2006) [30] | 209 | 209 | FACT-BRM | Clinical distinct groups using performance status |
| Eton, D.T. (2004) [31] | 771 | 128 to 643 | FACT-B | Performance status, physician assessment of current pain, and response to treatment |
| Granger, C.L. (2015) [34] | 69 | 69 | Physical Activity Scale For The Elderly (PASE) | No anchor used |
| Granger, C.L. (2015) [33] | 56 | 63 to 66 | 6-Minute Walk Distance | Physical functioning dimension of the QLQ-C30 |
| Hong, F. (2013) [35] | 765 | 627 | EORTC QLQ-C30 | Patient’s rating of change |
| Hui, D. (2016) [36] | 796 | 792 to 795 | Edmonton Symptom Assessment System (ESAS) | Patient’s rating of change |
| Jayadevappa, R. (2012) [37] | 602 | 528 | SF-36, UCLA Prostate Cancer Index (PCI) | A patient-reported physical signs/symptoms (more tired or worn out than usual) |
| Kemmler, G. (2010) [38] | 187 | 160 | EORTC QLQ-C30 | Patient’s rating of change |
| Lemieux, J. (2007) [39] | 235 | 133 | EORTC QLQ-C30, POMS, MAC, IES, PAIS, PAIN | No anchor used |
| Liu, H. (2015) [40] | 2440 | ≤ 246 | 2 single-item questions | Patient’s rating of change |
| Maringwa, J.T (2011) [41] | 941 | 420 to 572 | EORTC QLQ-C30, QLQ-BN20 | Performance status; MMSE |
| Maringwa, J.T (2011) [41] | 812 | 410 to 519 | EORTC QLQ-C30 | Performance status; weight change |
| Mathias, S.D. (2011) [42] | 2049 | 1564 | Brief Pain Inventory-Short Form (BPI-SF) | BPI-SF current pain and EQ-5D index score |
| Mouysset, J.L. (2016) [43] | 1262 | 510 | FACT-F | VAS of fatigue |
| Ousmen, A. (2016) [62] | 381 | 74 to 260 | EORTC QLQ-C30; QLQ-BR23 | Patient’s rating of change |
| Pickard, A.S. (2007) [44] | 534 | 534 | EQ-5D | Performance status |
| Purcell, A. (2010) [45] | 210 | 157 to 199 | MFI-20 | VAS of the EQ-5D; performance status; treatment impact on fatigue |
| Raman, S. (2016) [46] | 298 | 201 to 204 | EORTC QLQ-BM22, QLQ-C15-PAL | Global HRQOL dimension of the QLQ-C15 PAL |
| Raman, S. (2018) [47] | 850 | 360 to 375 | EORTC QLQ-C30, BPI | Global HRQOL dimension of the QLQ-C30 |
| Sagberg, L.M. (2014) [48] | 173 | 142 to 164 | EQ-5D 3 L | Performance status |
| Shun, S.C (2007) [49] | 243 | 148 | 3 fatigue instruments | Patient’s rating of change |
| Skolarus, T.A. (2015) [50] | 1201 | 1201 | EPIC-26 | Item from the service satisfaction scale for cancer care scale |
| Steel, J. L. (2006) [51] | 158 | 158 | FACT-HEP | Alpha-fetoprotein, alkaline phosphate and hemoglobin levels, survival |
| Tamminga, S.J. (2014) [52] | 53 | 43 | Work Limitations Questionnaire (WLQ) | Patient’s rating of change |
| Tsiplova, K. (2016) [53] | 3770 | 3765 | EQ-5D | Global health question |
| Tuomi, L. (2016) [54] | 126 | 119 | Swedish self-evaluation of communication experiences after laryngeal cancer (S-SECEL) | Acceptability of speech in a social context |
| Wong, E. (2015) [55] | 99 | 77 to 99 | EORTC QLQ-BN20 | Item 30 of the QLQ-C30 or 15 of QLQ-C15 PAL |
| Wong, K. (2013) [56] | 414 | 153 to 233 | Brief Pain Inventory (BPI) | Pain score of the BPI |
| Wright, P. (2008) [57] | 276 | 187 | Social Difficulty Inventory | Social functioning dimension of the QLQ-C30 |
| Yost, K.J. (2005) [58] | 200 | 144 to 164 | FACT-BRM | Patient’s rating of change; performance status |
| Yost, K.J. (2005) [58] | 60 | 60 to 568 | FACT-C | Performance status |
| Yost, K.J. (2011) [59] | 101 | 88 to 101 | PROMIS-cancer scales | Patient’s rating of change; performance status; 21 other anchors |
| Zeng, L. (2012) [61] | 400 | 88 to 93 | EORTC QLQ-C30, QLQ-BM22 | Performance status |