Table 1.
Baseline characteristics
| Characteristics | Before PS match | p value | After PS match | p value | ||
|---|---|---|---|---|---|---|
| AAβ (n = 872) | NO-AAβ (n = 1833) | AAβ (n = 226) | NO-AAβ (n = 452) | |||
| Demographic | ||||||
| Age (years) | 68 (58–78) | 63 (55–76) | < 0.001 | 64 (55–77) | 66 (55–78) | 0.56 |
| Male sex | 582 (66.7) | 1336 (72.9) | 0.001 | 155 (68.6) | 319 (70.6) | 0.60 |
| BMI (kg/m2) | 25.6 (23.4–27.9) | 25.0 (22.9–27.4) | 0.001 | 25.4 (23.4–28.0) | 25.3 (22.9–27.6) | 0.28 |
| Initial presentation | ||||||
| SBP (mmHg) | 133 (122–149) | 126 (112–140) | < 0.001 | 130 (117–144) | 130 (118–144) | 0.93 |
| DBP (mmHg) | 74 (67–82) | 72 (65–80) | < 0.001 | 74 (67–83) | 74 (65–82) | 0.50 |
| Killip class ≥ 2 | 318 (36.5) | 531 (29) | < 0.001 | 65 (28.8) | 130 (28.8) | 0.23 |
| Past history | ||||||
| HT | 836 (95.9) | 940 (51.4) | < 0.001 | 191 (84.5) | 382 (84.5) | 1 |
| DM | 376 (43.1) | 550 (30.0) | < 0.001 | 29 (12.8) | 67 (14.8) | 0.48 |
| Dyslipidemia | 414 (47.6) | 689 (38.2) | < 0.001 | 78 (34.5) | 146 (32.3) | 0.56 |
| Smoking | 460 (52.8) | 1144 (62.4) | < 0.001 | 122 (54.0) | 262 (58.2) | 0.29 |
| CRF | 96 (11) | 101 (5.5) | < 0.001 | 14 (6.19) | 23 (5.09) | 0.55 |
| HF | 24 (2.78) | 11 (0.61) | < 0.001 | 2 (0.88) | 2 (0.44) | 0.48 |
| CAD | 459 (52.7) | 594 (32.7) | < 0.001 | 35 (15.5) | 71 (15.7) | 0.94 |
| Previous MI | 149 (17.1) | 172 (9.5) | < 0.001 | 22 (9.7) | 35 (7.8) | 0.38 |
| Previous PCI | 219 (25.1) | 194 (10.6) | < 0.001 | 18 (8.0) | 17 (3.8) | 0.02 |
| Stroke | 188 (21.6) | 285 (15.6) | < 0.001 | 41 (18.1) | 81 (17.9) | 0.94 |
| Laboratory finding | ||||||
| TC (mmol/L) | 4.10 (3.44–4.78) | 4.42 (3.77–5.08) | < 0.001 | 4.27 (3.61–4.86) | 4.42 (3.84–5.04) | 0.01 |
| TG (mmol/L) | 1.35 (0.99–1.97) | 1.40 (1.0–1.97) | 0.287 | 1.27 (0.99–1.87) | 1.38 (0.99–1.96) | 0.21 |
| LDL-C (mmol/L) | 2.33 (1.83–2.80) | 2.55 (2.07–3.06) | < 0.001 | 2.41 (1.96–2.93) | 2.60 (2.13–3.01) | 0.004 |
| pNT-proBNP (ng/L) | 2035 (587–7645) | 1637 (557–5475) | 0.01 | 1712 (674–5693) | 1701 (587–5598) | 0.91 |
| Scr (μmol/L) | 88.3 (75.0–106.8) | 83.5 (74.0–96.0) | < 0.001 | 84.2 (74.4–101.6) | 84.5 (75.0–95.7) | 0.51 |
| GFR (mL/min | 72.2 (55.2–87.3) | 80.5 (64.1–95.1) | < 0.001 | 74.7 (59.8–89.3) | 78.1 (63.6–93.9) | 0.14 |
| Hospital course | ||||||
| STEMI | 326 (37.4) | 980 (53.5) | < 0.001 | 113 (50) | 258 (57.1) | 0.08 |
| NSTEMI | 546 (62.6) | 853 (46.5) | < 0.001 | 113 (50) | 194 (42.9) | 0.08 |
| E-PCI | 191 (29.7) | 534 (36.5) | 0.003 | 53 (29.0) | 139 (37.6) | 0.046 |
AAβ ACEI/ARB/β-B, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HT hypertension, DM diabetes mellitus, CRF chronic renal failure, HF heart failure, CAD coronary artery disease, MI myocardial infarction, PCI percutaneous coronary intervention, TC total cholesterol, TG triglyceride, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, NT-proBNP N-terminal pro-brain natriuretic peptide, GFR glomerular filtration rate, STEMI ST-segment elevation AMI, NSTEMI non-ST-segment elevation AMI, E-PCI emergency percutaneous coronary intervention
p values for comparisons between the two groups. Significance level was 0.05