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. 2018 Dec 11;16:102. doi: 10.1186/s12951-018-0428-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Imaging of cancer cell morphology and measuring the mechanical properties of cancer cells by AFM. a Representative AFM height image. b Representative AFM deflection image. c 3D distribution of cell height. The force curve is used to calculate mechanical properties. d Image representing Young’s modulus distribution. e Image representing adhesion force distribution. f Image representing stiffness distribution. Parameters are displayed as colors. The results of morphology observation and mechanical properties measurement of the cell were from our study group