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. 2018 Dec 11;18:1364. doi: 10.1186/s12889-018-6235-6

Table 2.

Characteristics of the participants according to new vaccine delays (2–4-6 and 12 months), 2006–2016 (N = 7183)a

Vaccine delays
DTaP1 (2 month visit) DTaP2 (4 month visit) DTaP3 (6 month visit) Measles (12 month visit)
Frequencyb % P valuec Frequencyb % P valuec Frequencyb % P valuec Frequencyb % P valuec
Dose not administered 99 130 181 272
Total vaccine delays 386/7084d 5.4% 941/7053d 13.3% 1617/7002d 23.1% 1634/6911d 23.6%
 New vaccine delays 386/386 100% 627/941 66.7% 807/1617 49.9% 986/1634 60.3%
Denominator used for the analysis N = 7084 N = 6682e N = 6039e N = 5166e
Characteristics
Year of survey:
 2006 53/791 6.7% 0.003 78/738 10.6% 0.04 116/659 17.6% 0.001 149/535 27.9% < 0.0001
 2008 67/1211 5.5% 104/1144 9.1% 138/1039 13.3% 229/891 25.7%
 2010 76/1160 6.6% 117/1081 10.8% 145/962 15.1% 165/804 20.5%
 2012 88/1381 6.4% 133/1286 10.3% 153/1149 13.3% 181/982 18.4%
 2014 58/1321 4.4% 109/1259 8.7% 132/1145 11.5% 140/1003 14.0%
 2016 44/1220 3.6% 86/1174 7.3% 123/1085 11.3% 122/951 12.8%
Sex:
 Female 188/3445 5.5% 0.98 316/3250 9.7% 0.35 404/2927 13.8% 0.34 449/2486 18.1% 0.07
 Male 198/3639 7.5% 311/3432 9.1% 403/3112 12.9% 537/2680 20.0%
Maternal age at child’s birth
  < 20 years 3/71 4.2% 0.03 6/68 8.8% 0.74 8/61 13.1% 0.49 7/52 13.5% 0.47
 20–29 years 168/3107 5.4% 286/2929 9.8% 334/2635 12.7% 426/2266 18.8%
 30–39 years 192/3685 5.2% 318/3487 9.1% 434/3163 13.7% 520/2701 19.3%
  ≥ 40 years 20/197 10.2% 14/177 7.9% 26/162 16.0% 31/135 23.0%
 Unknown / missing 3/24 12.5% 3 /21 14.3% 5/18 27.8% 2/13 15.4%
Mother’s languagef:
 French 250/4936 5.1% 0.03 400/4673 8.6% 0.004 525/4260 12.3% 0.001 655/3693 17.7% 0..04
 English 32/389 8.2% 36/355 10.1% 32/317 10.1% 66/279 23.7%
 Other 47/942 5.0% 107/894 12.0% 131/787 16.6% 113/647 17.5%
 Unknown / missing 57/817 7.0% 84/760 11.1% 119/675 17.6% 152/547 27.8%
Mother’s originf:
 Canada 210/4066 5.2% 0.91 318/3845 8.3% 0.0004 415/3516 11.8% 0.0002 501/3063 16.4% 0.64
 Other 52/990 5.3% 122/933 13.1% 134/809 16.6% 104/666 15.6%
 Unknown / missing 124/2028 6.1% 187/1904 9.8% 258/1714 15.1% 381/1437 26.5%
Maternal level of education:
  < High school 40/490 8.2% 0.0008 55/449 12.2% < 0.0001 77/390 19.7% 0.0013 63/303 20.8% 0.84
 High school 101/1548 6.5% 175/1445 12.1% 172/1266 13.6% 209/1078 19.4%
 College 110/2074 5.3% 174/1958 8.9% 220/1780 12.4% 290/1533 18.9%
 University 129/2925 4.4% 218/2790 8.9% 332/2568 12.9% 417/2224 18.8%
 Unknown / missing 6/47 12.8% 5/40 12.5% 6/35 17.1% 7/28 25.0%
Child rank:
 First 118/3118 3.8% < 0.0001 206/2995 6.9% < 0.0001 300/2784 10.8% < 0.0001 437/2465 17.7% 0.01
  ≥ 2 260/3885 6.7% 405/3615 11.2% 501/3200 15.7% 542/2654 20.4%
 Unknown / missing 8/81 9.9% 16/72 22.2% 6/55 10.9% 7/47 14.3%
Daycare attendance:
 Yes 251/5461 4.6% < 0.0001 461/5201 8.9% 0.008 618/4732 13.1% 0.20 760/4066 18.7% 0.21
 No 132/1583 8.3% 161/1444 11.1% 184/1275 14.4% 219/1075 20.4%
 Unknown / missing 3/40 7.5% 5/37 13.5% 5/32 15.6% 7/25 28.0%
Child with a chronic disease:
 Yes 23/394 7.8% 0.69 46/369 12.5% 0.04 53/323 16.4% 0.09 65/265 24.5% 0.02
 No 357/6650 5.4% 577/6279 9.2% 747/5686 13.1% 917/4878 18.8%
 Unknown / missing 6/40 15.0% 4/34 11.8% 7/30 23.3% 4/23 17.4%
Gestational age at birth:
  < 37 weeks 35/511 6.8% 0.14 56/476 11.8% 0.04 60/419 14.3% 0.48 86/354 24.3% 0.009
  ≥ 37 weeks 336/6338 5.3% 534/5988 8.9% 713/5439 13.1% 870/4667 18.6%
 Unknown / missing 15/235 6.4% 37/218 17.0% 34/181 18.8% 30/145 20.7%
Living with a partner
 Yes 339/6504 5.2% 0.004 559/6152 9.1% 0.01 731/5580 13.1% 0.28 901/4795 18.8% 0.11
 No 40/480 8.3% 86/438 19.6% 57/379 15.0% 70/312 22.4%
 Unknown / missing 7/100 7.0% 12/92 13.0% 19/80 23.8% 15/59 25.4%
Birth attendantf:
 Physician 221/4791 4.6% < 0.0001 418/4557 9.2% 0.55 516/4126 12.5% 0.05 572/3567 16.0% 0.30
 Midwife or other professionnal 38/252 15.1% 22/212 10.4% 33/189 17.5% 29/151 19.2%
 Unknown / missing 127/2041 6.2% 187/1914 9.8% 258/1724 15.0% 385/1448 26.6%
Vaccine provider (at 2 months):
 Public health clinics 277/5033 5.5% 0.68 468/4742 9.9% 0.02 595/4264 14.0% 0.02 610/3629 16.8% < 0.0001
 Medical clinic/Hospital 105/1999 5.3% 153/1892 8.1% 204/1734 11.8% 367/1504 24.4%
 Unknown / missing 4/52 7.7% 6/48 12.5% 8/41 19.5% 9/33 27.3%
Main vaccine provider (all vaccines):
 Public health clinics only 574/3473 16.5% < 0.0001
 Medical clinic/Hospital or both settings 406/1669 24.3%
 Unknown / missing 6/24 25.0%
Missed opportunities at the 2-month visit:
 Yes 48/217 22.1% < 0.0001 20/166 12.0% < 0.0001 27/146 18.5% 0.07 27/114 23.7% 0.21
 No 338/6867 4.9% 607/6516 9.3% 780/5893 13.2% 959/5052 19.0%
Missed opportunities at the 12-month visit:
 Yes 227/702 32.3% < 0.0001
 No 759/4464 17.0%

a Analysis limited to children born in Quebec. Both cohorts included / b Correspond to the proportion of children who experienced new vaccine delays by each variable category / cChi-square test, unknown and missing excluded

dCorrespond to the difference between 7183 and the number of children with a dose not administered

eFor DTaP2 the 6682 represent 6698 children without vaccine delay for DTaP1 minus 16 children who had not received DTaP 2. For DTaP3 the 6039 represent 6055 children without vaccine delay for DTaP1 and DTaP2 minus 16 children who had not received DTaP 3. For MMR1 the 5166 represent 5232 children without vaccine delay for DTaP1, DTaP2 and DTaP3 minus 66 children who had not received MMR1

fThese variables were not collected in 2006 and 2008