Table 2.
Vaccine delays | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
DTaP1 (2 month visit) | DTaP2 (4 month visit) | DTaP3 (6 month visit) | Measles (12 month visit) | |||||||||
Frequencyb | % | P valuec | Frequencyb | % | P valuec | Frequencyb | % | P valuec | Frequencyb | % | P valuec | |
Dose not administered | 99 | 130 | 181 | 272 | ||||||||
Total vaccine delays | 386/7084d | 5.4% | 941/7053d | 13.3% | 1617/7002d | 23.1% | 1634/6911d | 23.6% | ||||
New vaccine delays | 386/386 | 100% | 627/941 | 66.7% | 807/1617 | 49.9% | 986/1634 | 60.3% | ||||
Denominator used for the analysis | N = 7084 | N = 6682e | N = 6039e | N = 5166e | ||||||||
Characteristics | ||||||||||||
Year of survey: | ||||||||||||
2006 | 53/791 | 6.7% | 0.003 | 78/738 | 10.6% | 0.04 | 116/659 | 17.6% | 0.001 | 149/535 | 27.9% | < 0.0001 |
2008 | 67/1211 | 5.5% | 104/1144 | 9.1% | 138/1039 | 13.3% | 229/891 | 25.7% | ||||
2010 | 76/1160 | 6.6% | 117/1081 | 10.8% | 145/962 | 15.1% | 165/804 | 20.5% | ||||
2012 | 88/1381 | 6.4% | 133/1286 | 10.3% | 153/1149 | 13.3% | 181/982 | 18.4% | ||||
2014 | 58/1321 | 4.4% | 109/1259 | 8.7% | 132/1145 | 11.5% | 140/1003 | 14.0% | ||||
2016 | 44/1220 | 3.6% | 86/1174 | 7.3% | 123/1085 | 11.3% | 122/951 | 12.8% | ||||
Sex: | ||||||||||||
Female | 188/3445 | 5.5% | 0.98 | 316/3250 | 9.7% | 0.35 | 404/2927 | 13.8% | 0.34 | 449/2486 | 18.1% | 0.07 |
Male | 198/3639 | 7.5% | 311/3432 | 9.1% | 403/3112 | 12.9% | 537/2680 | 20.0% | ||||
Maternal age at child’s birth | ||||||||||||
< 20 years | 3/71 | 4.2% | 0.03 | 6/68 | 8.8% | 0.74 | 8/61 | 13.1% | 0.49 | 7/52 | 13.5% | 0.47 |
20–29 years | 168/3107 | 5.4% | 286/2929 | 9.8% | 334/2635 | 12.7% | 426/2266 | 18.8% | ||||
30–39 years | 192/3685 | 5.2% | 318/3487 | 9.1% | 434/3163 | 13.7% | 520/2701 | 19.3% | ||||
≥ 40 years | 20/197 | 10.2% | 14/177 | 7.9% | 26/162 | 16.0% | 31/135 | 23.0% | ||||
Unknown / missing | 3/24 | 12.5% | 3 /21 | 14.3% | 5/18 | 27.8% | 2/13 | 15.4% | ||||
Mother’s languagef: | ||||||||||||
French | 250/4936 | 5.1% | 0.03 | 400/4673 | 8.6% | 0.004 | 525/4260 | 12.3% | 0.001 | 655/3693 | 17.7% | 0..04 |
English | 32/389 | 8.2% | 36/355 | 10.1% | 32/317 | 10.1% | 66/279 | 23.7% | ||||
Other | 47/942 | 5.0% | 107/894 | 12.0% | 131/787 | 16.6% | 113/647 | 17.5% | ||||
Unknown / missing | 57/817 | 7.0% | 84/760 | 11.1% | 119/675 | 17.6% | 152/547 | 27.8% | ||||
Mother’s originf: | ||||||||||||
Canada | 210/4066 | 5.2% | 0.91 | 318/3845 | 8.3% | 0.0004 | 415/3516 | 11.8% | 0.0002 | 501/3063 | 16.4% | 0.64 |
Other | 52/990 | 5.3% | 122/933 | 13.1% | 134/809 | 16.6% | 104/666 | 15.6% | ||||
Unknown / missing | 124/2028 | 6.1% | 187/1904 | 9.8% | 258/1714 | 15.1% | 381/1437 | 26.5% | ||||
Maternal level of education: | ||||||||||||
< High school | 40/490 | 8.2% | 0.0008 | 55/449 | 12.2% | < 0.0001 | 77/390 | 19.7% | 0.0013 | 63/303 | 20.8% | 0.84 |
High school | 101/1548 | 6.5% | 175/1445 | 12.1% | 172/1266 | 13.6% | 209/1078 | 19.4% | ||||
College | 110/2074 | 5.3% | 174/1958 | 8.9% | 220/1780 | 12.4% | 290/1533 | 18.9% | ||||
University | 129/2925 | 4.4% | 218/2790 | 8.9% | 332/2568 | 12.9% | 417/2224 | 18.8% | ||||
Unknown / missing | 6/47 | 12.8% | 5/40 | 12.5% | 6/35 | 17.1% | 7/28 | 25.0% | ||||
Child rank: | ||||||||||||
First | 118/3118 | 3.8% | < 0.0001 | 206/2995 | 6.9% | < 0.0001 | 300/2784 | 10.8% | < 0.0001 | 437/2465 | 17.7% | 0.01 |
≥ 2 | 260/3885 | 6.7% | 405/3615 | 11.2% | 501/3200 | 15.7% | 542/2654 | 20.4% | ||||
Unknown / missing | 8/81 | 9.9% | 16/72 | 22.2% | 6/55 | 10.9% | 7/47 | 14.3% | ||||
Daycare attendance: | ||||||||||||
Yes | 251/5461 | 4.6% | < 0.0001 | 461/5201 | 8.9% | 0.008 | 618/4732 | 13.1% | 0.20 | 760/4066 | 18.7% | 0.21 |
No | 132/1583 | 8.3% | 161/1444 | 11.1% | 184/1275 | 14.4% | 219/1075 | 20.4% | ||||
Unknown / missing | 3/40 | 7.5% | 5/37 | 13.5% | 5/32 | 15.6% | 7/25 | 28.0% | ||||
Child with a chronic disease: | ||||||||||||
Yes | 23/394 | 7.8% | 0.69 | 46/369 | 12.5% | 0.04 | 53/323 | 16.4% | 0.09 | 65/265 | 24.5% | 0.02 |
No | 357/6650 | 5.4% | 577/6279 | 9.2% | 747/5686 | 13.1% | 917/4878 | 18.8% | ||||
Unknown / missing | 6/40 | 15.0% | 4/34 | 11.8% | 7/30 | 23.3% | 4/23 | 17.4% | ||||
Gestational age at birth: | ||||||||||||
< 37 weeks | 35/511 | 6.8% | 0.14 | 56/476 | 11.8% | 0.04 | 60/419 | 14.3% | 0.48 | 86/354 | 24.3% | 0.009 |
≥ 37 weeks | 336/6338 | 5.3% | 534/5988 | 8.9% | 713/5439 | 13.1% | 870/4667 | 18.6% | ||||
Unknown / missing | 15/235 | 6.4% | 37/218 | 17.0% | 34/181 | 18.8% | 30/145 | 20.7% | ||||
Living with a partner | ||||||||||||
Yes | 339/6504 | 5.2% | 0.004 | 559/6152 | 9.1% | 0.01 | 731/5580 | 13.1% | 0.28 | 901/4795 | 18.8% | 0.11 |
No | 40/480 | 8.3% | 86/438 | 19.6% | 57/379 | 15.0% | 70/312 | 22.4% | ||||
Unknown / missing | 7/100 | 7.0% | 12/92 | 13.0% | 19/80 | 23.8% | 15/59 | 25.4% | ||||
Birth attendantf: | ||||||||||||
Physician | 221/4791 | 4.6% | < 0.0001 | 418/4557 | 9.2% | 0.55 | 516/4126 | 12.5% | 0.05 | 572/3567 | 16.0% | 0.30 |
Midwife or other professionnal | 38/252 | 15.1% | 22/212 | 10.4% | 33/189 | 17.5% | 29/151 | 19.2% | ||||
Unknown / missing | 127/2041 | 6.2% | 187/1914 | 9.8% | 258/1724 | 15.0% | 385/1448 | 26.6% | ||||
Vaccine provider (at 2 months): | ||||||||||||
Public health clinics | 277/5033 | 5.5% | 0.68 | 468/4742 | 9.9% | 0.02 | 595/4264 | 14.0% | 0.02 | 610/3629 | 16.8% | < 0.0001 |
Medical clinic/Hospital | 105/1999 | 5.3% | 153/1892 | 8.1% | 204/1734 | 11.8% | 367/1504 | 24.4% | ||||
Unknown / missing | 4/52 | 7.7% | 6/48 | 12.5% | 8/41 | 19.5% | 9/33 | 27.3% | ||||
Main vaccine provider (all vaccines): | ||||||||||||
Public health clinics only | 574/3473 | 16.5% | < 0.0001 | |||||||||
Medical clinic/Hospital or both settings | 406/1669 | 24.3% | ||||||||||
Unknown / missing | 6/24 | 25.0% | ||||||||||
Missed opportunities at the 2-month visit: | ||||||||||||
Yes | 48/217 | 22.1% | < 0.0001 | 20/166 | 12.0% | < 0.0001 | 27/146 | 18.5% | 0.07 | 27/114 | 23.7% | 0.21 |
No | 338/6867 | 4.9% | 607/6516 | 9.3% | 780/5893 | 13.2% | 959/5052 | 19.0% | ||||
Missed opportunities at the 12-month visit: | ||||||||||||
Yes | 227/702 | 32.3% | < 0.0001 | |||||||||
No | 759/4464 | 17.0% |
a Analysis limited to children born in Quebec. Both cohorts included / b Correspond to the proportion of children who experienced new vaccine delays by each variable category / cChi-square test, unknown and missing excluded
dCorrespond to the difference between 7183 and the number of children with a dose not administered
eFor DTaP2 the 6682 represent 6698 children without vaccine delay for DTaP1 minus 16 children who had not received DTaP 2. For DTaP3 the 6039 represent 6055 children without vaccine delay for DTaP1 and DTaP2 minus 16 children who had not received DTaP 3. For MMR1 the 5166 represent 5232 children without vaccine delay for DTaP1, DTaP2 and DTaP3 minus 66 children who had not received MMR1
fThese variables were not collected in 2006 and 2008