Figure 2.

Galectins regulate B cell development, activation, and differentiation. Depicted are published roles of galectins at various stages of differentiation, as well as reported expression of galectins and galectin-binding glycans. Orange asterisks (*) indicate findings described in human B cells, and blue asterisks (*) indicate findings observed in mice. Bone marrow B cells (28–34, 37, 60); naïve B cells (38, 43, 45, 56, 57); anergic B cells (37, 68); GC B cells (45, 51); memory B cells (37, 40, 45–50, 58); plasmablasts and plasma cells (37, 39, 59, 60).