Fig. 4.

CdCl₂ induced the expression of progesterone receptors (PR) in an ER-dependent manner. The expression of (A) PRA and (B) PRB in the presence of ICI 182,780 and without ICI 182,780 were assayed using western blotting method in CdCl₂-treated cells. Quantitative analysis of the expression of PRA in (C) OVCAR3, (D), SKOV3 cells; PRB in (E) OVCAR3, and (F) in SKOV3 cells were performed by image j software. Asterisks show significant differences between CdCl₂-treated cells in the presence of ICI 182,780 and corresponding cells without ICI 182,780 (*P< 0.05, **P< 0.01, and ***P< 0.001). CC, CdCl₂; ICI, ICI 182,780.