Fig. 3.

Inhibitory effect of Helicteres isora fruit extracts on lipo-polysaccharide (LPS)-stimulated (A) prostaglandin E2 (PGE-2), (B) cyclooxygenase-2 (COX-2), and (C) tumor necrosis factor-alpha (TNF-α) production in THP-1 cell line compared with 10 and 100 μg/mL dexamethasone and 0.02 μg/mL celecoxib. Each value indicates the mean ± SD of three parallel measurements. EtOH, ethanol extract; DCM, dichloromethane extract; DI, distilled water extract; HEX, hexane extract. *The significant difference was assumed at 0.05 level when compared with other extracts.