Table 3.

Severity Scores on Admission to the ICU, Maximum Number of Organ Failure, and Mortality Rates According to Sepsis Status

		Severity Scores, Mean ± SD				Mortality Rates, % (95% CI)
Category	n	SAPS II	SOFA	ICU LOSa, Median [IQR]	No. of Organ Failures Median [IQR]	ICUb	In-Hospitalc
Onset of Sepsis
Within the first 48 hoursd	2209	50.5 ± 16.8	9.2 ± 3.9	5 [2–10]	3 [2–4]	26.0 (24.2–27.9)	35.8 (33.8–37.9)
Later	764	45.4 ± 15.5e	7.5 ± 3.8e	12 [6–19]e	3 [2–4]	25.1 (22.0–28.3)	33.8 (30.3–37.2)
Severity of Sepsis on ICU Admission
No sepsisd	8261	37.8 ± 17.5	5.3 ± 4.1	3 [1–5]	1 [0–2]	13.6 (12.9–14.4)	19.0 (18.1–19.9)
Sepsis without shock	822	46.2 ± 15.4e	7.4 ± 2.9e	5 [2–9]e	2 [1–3]e	20.1 (17.4–22.9)e	30.3 (27.1–33.6)e
Septic shock	986	55.1 ± 17.2e	11.3 ± 3.6e	5 [2–11]e	3 [2–4]e	33.7 (30.7–36.7)e	43.0 (39.9–46.2)e
Severity of Sepsis During ICU Stay
No sepsisd	7096	36.4 ± 17.4	4.9 ± 4.0	2 [1–4]	1 [0–2]	12.1 (11.3–12.8)	16.7 (15.8–17.6)
Sepsis without shock	1292	44.6 ± 15.3e	7.0 ± 3.2e	6 [3–11]e	2 [1–3]e	14.3 (12.4–16.2)f	23.6 (21.3–26.0)e
Septic shock	1681	52.7 ± 16.7e	10.1 ± 3.9e	7 [3–14]e	3 [2–4]e	34.6 (32.3–36.9)e	44.2 (41.7–46.6)e

Abbreviations: CI, confidence interval; ICU, intensive care unit; IQR, interquartile; LOS, length of stay; SAPS, simplified acute physiology score; SD, standard deviation; SOFA, sequential organ failure assessment score.

Missing observations: ^a489, ^b401, ^c797.

^dThe reference group.

^e P < .01 among groups.

^f P < .05 among groups.