Table 4.
Outcome According to Isolated Microorganisms in Patients With Sepsis (n = 2973)
| Risk Factor | ICU Mortality, n (%) |
Hospital Mortality, n (%) | Crude Risk of In- Hospital Death OR (95% CI) |
P Value |
|---|---|---|---|---|
| Gram-positive | 267 (26.2) | 360 (36.0) | 1.05 (0.89–1.23) | .55 |
| Staphylococcus aureus methicillin sensitive | 71 (28.0) | 89 (36.0) | 1.04 (0.79–1.36) | .80 |
| MRSA | 36 (24.2) | 51 (34.7) | 0.97 (0.69–1.38) | .87 |
| Staphylococcus, coagulase negative | 129 (26.0) | 184 (37.9) | 1.14 (0.93–1.40) | .20 |
| Streptococcus, D group | 16 (19.3) | 22 (27.5) | 0.69 (0.42–1.13) | .14 |
| Streptococcus, others | 57 (26.1) | 77 (35.8) | 1.02 (0.77–1.37) | .87 |
| Other Gram-positive cocci | 9 (19.6) | 13 (29.5) | 0.77 (0.40–1.47) | .42 |
| Gram negative | 364 (26.6) | 492 (37.0) | 1.15 (0.99–1.34) | .07 |
| Escherichia coli | 114 (24.7) | 162 (36.0) | 1.04 (0.84–1.28) | .74 |
| Enterobacter spp | 45 (24.1) | 67 (36.8) | 1.07 (0.79–1.46) | .66 |
| Klebsiella spp | 92 (26.4) | 128 (37.9) | 1.13 (0.90–1.43) | .29 |
| Acinetobacter spp | 88 (37.0) | 110 (48.0) | 1.78 (1.36–2.33) | <.01 |
| Proteus spp | 28 (23.1) | 40 (33.6) | 0.92 (0.63–1.36) | .69 |
| Pseudomonas spp | 100 (30.1) | 131 (40.4) | 1.28 (1.01–1.62) | .04 |
| Gram negative, others | 82 (25.9) | 110 (35.7) | 1.02 (0.80–1.31) | .87 |
| Anaerobes | 23 (29.1) | 31 (39.7) | 1.22 (0.77–1.93) | .41 |
| Other bacteria | 6 (33.3) | 7 (38.9) | 1.17 (0.45–3.02) | .75 |
| Fungi | 77 (29.2) | 107 (41.6) | 1.34 (1.04–1.75) | .03 |
| Candida albicans | 49 (26.8) | 71 (39.9) | 1.23 (0.90–1.68) | .19 |
| Candida non-albicans | 26 (29.2) | 38 (43.7) | 1.44 (0.93–2.21) | .10 |
| Fungi, others | 16 (36.4) | 20 (45.5) | 1.54 (0.85–2.80) | .16 |
| Viruses and parasites | 16 (28.1) | 21 (36.8) | 1.07 (0.62–1.84) | .81 |
Abbreviations: CI, confidence interval; ICU, intensive care unit; MRSA, methicillin-resistant Staphylococcus aureus; OR, odds ratio.