Table 2.
Changes in Antimicrobial Susceptibility in Selected Organisms Between the Preintervention and the Intervention Periodsa
| Organisms and Antimicrobials | Isolates Resistant in the Preintervention Period (%) |
Isolates Resistant in the Intervention Period (%) | P |
|---|---|---|---|
| Escherichia coli | |||
| Cefepime | 101/866 (11.7)b | 579/3822 (15.1) | .01 |
| Cefotaxime | 201/1601 (12.6) | 635/3822 (16.6) | <.001 |
| Levofloxacin | 395/1601 (24.7) | 1113/3822 (29.1) | <.001 |
| Enterobacter cloacae | |||
| Meropenem | 0/136 (0)b | 2/551 (0.7) | N/A |
| Piperacillin/tazobactam | 40/136 (29.4)b | 90/551 (16.3) | <.001 |
| Cefepime | 16/136 (11.8)b | 44/551 (8.0) | .16 |
| Pseudomonas aeruginosa | |||
| Imipenem-cilastatin | 80/995 (8.0) | 147/2344 (6.3) | .06 |
| Piperacillin/tazobactam | 90/995 (9.5) | 251/2344 (10.7) | .15 |
| Cefepime | 156/995 (15.7) | 250/2344 (10.7) | <.001 |
| Staphylococcus aureus | |||
| Methicillin | 386/1527 (25.3) | 804/3348 (24.0) | 0.34 |
Abbreviations: N/A, not available.
aThe preintervention period was from April 2012 to March 2014, and the intervention period was from April 2014 to March 2018.
bSusceptibility data from April 2012 to March 2013 were not available.