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. 2018 Dec 7;10:6779–6790. doi: 10.2147/CMAR.S185601

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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D6D inhibitor sensitized glioblastoma cells to radiation in vitro.

Notes: (A and B) MTS assay of U-87 MG and LN-229 cells treated with vehicle control, SC-26196, radiation, or their combination at indicated dose. (C and D) Colony formation assay of U-87 MG and LN-229 cells treated with vehicle control, SC-26196, radiation, or their combination at the indicated doses. (E and F) Apoptosis analysis (annexin V-FITC/PI double staining) of U-87 MG and LN-229 cells treated with vehicle control, SC-26196, radiation, or their combination at the indicated doses. All quantification data are represented as mean ± SD with at least three separate experiments. The data in control treatment group were normalized to 100%. *Significant difference with P<0.05.

Abbreviation: D6D, delta-6-desaturase.